@article {49,
	title = {Qualitative modelling of regulated metabolic pathways: application to the tryptophan biosynthesis in E.coli.},
	journal = {Bioinformatics (Oxford, England)},
	volume = {21 Suppl 2},
	year = {2005},
	month = {2005 Sep 1},
	pages = {ii190-6},
	abstract = {The integrated dynamical modelling of mixed metabolic/genetic networks constitutes one of the challenges of systems biology. Furthermore, as most of available data about genetic and metabolic regulations are qualitative, there is a pressing need for rigorous qualitative mathematical approaches.},
	keywords = {Computer Simulation, Escherichia coli, Escherichia coli Proteins, Gene Expression Regulation, Models, Biological, Neural Networks (Computer), Signal Transduction, Tryptophan},
	issn = {1367-4811},
	author = {Sim{\~a}o, E and Remy, E and Thieffry, D and Chaouiya, C}
}
