| Title | Toll signaling: the enigma variations. |
| Publication Type | Journal Article |
| Year of Publication | 2000 |
| Authors | Wasserman SA |
| Journal | Current opinion in genetics & development |
| Volume | 10 |
| Issue | 5 |
| Pagination | 497-502 |
| Date Published | 2000 Oct |
| ISSN | 0959-437X |
| Keywords | Animals, Drosophila, Drosophila Proteins, Humans, Insect Proteins, Membrane Glycoproteins, Receptors, Cell Surface, Receptors, Immunologic, Signal Transduction, Toll-Like Receptor 5, Toll-Like Receptors |
| Abstract | Experiments reported in the past year have revealed considerable diversity in Toll-mediated pathways for signal transduction in development and innate immunity. Rather than function as a well conserved signaling cassette, Toll receptors and associated factors have apparently evolved as a diverse set of configurations to defend against microbial infection in species ranging from plants to humans. |
| Alternate Journal | Curr. Opin. Genet. Dev. |