| Title | Qualitative modelling of regulated metabolic pathways: application to the tryptophan biosynthesis in E.coli. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Simão E, REMY E, Thieffry D, Chaouiya C |
| Journal | Bioinformatics (Oxford, England) |
| Volume | 21 Suppl 2 |
| Pagination | ii190-6 |
| Date Published | 2005 Sep 1 |
| ISSN | 1367-4811 |
| Keywords | Computer Simulation, Escherichia coli, Escherichia coli Proteins, Gene Expression Regulation, Models, Biological, Neural Networks (Computer), Signal Transduction, Tryptophan |
| Abstract | The integrated dynamical modelling of mixed metabolic/genetic networks constitutes one of the challenges of systems biology. Furthermore, as most of available data about genetic and metabolic regulations are qualitative, there is a pressing need for rigorous qualitative mathematical approaches. |
| Alternate Journal | Bioinformatics |