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Submitted
Corral-Jara KF, Chauvin C, Abou-Joudé W, Grandclaudon M, Naldi A, Soumelis V, Thieffry D.  Submitted.  Interplay between Smad2 and STAT5A is a critical determinant of IL- 17A/IL-17F differential expression..
Montagud A, Béal J, Tobalina L, Traynard P, Subramanian V, Szalai B, Alföldi R, Puskás L, Valencia A, Barillot E et al..  Submitted.  Patient-specific Boolean models of signaling networks guide personalized treatments.
2019
Sanchez-Villanueva JA, Rodriguez-Jorge O, Ramirez-Pliego O, Rosas-Salgado G, Abou-Jaoudé W, Hernandez C, Naldi A, Thieffry D, Santana MA.  2019.  Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation. PLoS One.
Rodríguez-Jorge O, Kempis-Calanis LA, Abou-Jaoudé W, Gutiérrez-Reyna DY, Hernandez C, Ramirez-Pliego O, Thomas-Chollier M, Spicuglia S, Santana MA, Thieffry D.  2019.  Cooperation between T cell receptor and Toll-like receptor 5 signaling for CD4+ T cell activation.. Science Signaling.
2018
Zanudo JGT, Steinway SN, Albert R.  2018.  Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer. Current Opinion in Systems Biology. 9:1-10.
2017
Collombet S, van Oevelen C, Sardina Ortega JL, Abou-Jaoudé W, Di Stefano B, Thomas-Chollier M, Graf T, Thieffry D.  2017.  Logical modeling of lymphoid and myeloid cell specification and transdifferentiation.. Proceedings of the National Academy of Sciences of the United States of America. 114(23):5792-5799. Abstract
2015
Abou-Jaoudé W, Monteiro PT, Naldi A, Grandclaudon M, Soumelis V, Chaouiya C, Thieffry D.  2015.  Model checking to assess T-helper cell plasticity. Frontiers in Bioengineering and Biotechnology. 2(86) Abstract
2010
Ayers KL, Thérond PP.  2010.  Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling.. Trends in cell biology. 20(5):287-98. Abstract
2009
Ayers KL, Rodriguez R, Gallet A, Ruel L, Thérond P.  2009.  Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila.. Developmental biology. 329(2):280-93. Abstract
Ayers KL, Rodriguez R, Gallet A, Ruel L, Thérond P.  2009.  Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila.. Developmental biology. 329(2):280-93. Abstract
Abou-Jaoudé W, Ouattara DA, Kaufman M.  2009.  From structure to dynamics: frequency tuning in the p53-Mdm2 network I. Logical approach.. Journal of theoretical biology. 258(4):561-77. Abstract
Sahin O, Fröhlich H, Löbke C, Korf U, Burmester S, Majety M, Mattern J, Schupp I, Chaouiya C, Thieffry D et al..  2009.  Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance. BMC systems biology. 3:1. Abstract
2008
Zhang R, Shah MV, Yang J, Nyland SB, Liu X, Yun JK, Albert R, Loughran TP.  2008.  Network model of survival signaling in large granular lymphocyte leukemia.. Proceedings of the National Academy of Sciences of the United States of America. 105(42):16308-13. Abstract
Aikin RA, Ayers KL, Thérond PP.  2008.  The role of kinases in the Hedgehog signalling pathway.. EMBO reports. 9(4):330-6. Abstract
2007
Saez-Rodriguez J, Simeoni L, Lindquist JA, Hemenway R, Bommhardt U, Arndt B, Haus U-U, Weismantel R, Gilles ED, Klamt S et al..  2007.  A logical model provides insights into T cell receptor signaling.. PLoS computational biology. 3(8):e163. Abstract
2003
Takeda K, Kaisho T, Akira S.  2003.  Toll-like receptors.. Annual review of immunology. 21:335-76. Abstract
2002
Eldar A, Dorfman R, Weiss D, Ashe H, Shilo B-Z, Barkai N.  2002.  Robustness of the BMP morphogen gradient in Drosophila embryonic patterning.. Nature. 419(6904):304-8. Abstract
2001
Amanai K, Jiang J.  2001.  Distinct roles of Central missing and Dispatched in sending the Hedgehog signal.. Development (Cambridge, England). 128(24):5119-27. Abstract
2000
Wang G, Amanai K, Wang B, Jiang J.  2000.  Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus.. Genes & development. 14(22):2893-905. Abstract
Anderson KV.  2000.  Toll signaling pathways in the innate immune response.. Current opinion in immunology. 12(1):13-9. Abstract
1999
Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A et al..  1999.  Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.. Molecular cell. 4(6):1029-40. Abstract
Waterman H, Levkowitz G, Alroy I, Yarden Y.  1999.  The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor.. The Journal of biological chemistry. 274(32):22151-4. Abstract
MENDOZA L, Thieffry D, Alvarez-Buylla ER.  1999.  Genetic control of flower morphogenesis in Arabidopsis thaliana: a logical analysis. Bioinformatics. 15(7):593-606.
1998
Vincent S, Wilson R, Coelho C, Affolter M, Leptin M.  1998.  The Drosophila protein Dof is specifically required for FGF signaling.. Molecular cell. 2(4):515-25. Abstract
Pepinsky RB, Zeng C, Wen D, Rayhorn P, Baker DP, Williams KP, Bixler SA, Ambrose CM, Garber EA, Miatkowski K et al..  1998.  Identification of a palmitic acid-modified form of human Sonic hedgehog.. The Journal of biological chemistry. 273(22):14037-45. Abstract


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